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Prometic reports its 2017 annual and special meeting of shareholders highlights PBI 4050 clinical efficacy demonstrated and confirmed in metabolic pre owned louis vuitton bracelet syndrome and type 2 diabetes, IPF and Alstrm syndrome patientsLAVAL, QC, May 10, 2017 /CNW Telbec/ Prometic Life Sciences Inc. (TSX: PLI) (OTCQX: PFSCF) ("Prometic" or the "Corporation") today reported the highlights from its 2017 louis vuitton bags denim blue annual and special meeting of shareholders and Board of Directors election results. With 3 successful phase 2 clinical trials confirming PBI 4050's positive clinical effects on the liver, the pancreas, the kidney and the lung, Prometic has significantly de risked the clinical program for PBI 4050 and its follow on analogues going forward. The pivotal phase 2/3 trials in idiopathic pulmonary fibrosis (IPF) and in chronic kidney diseases (CKD) are scheduled to commence in H2 2017 with minimal financial impact in 2017. Additional clinical data readouts will also become available in the coming months from the ongoing open label phase 2 Alstrm syndrome. Plasminogen is on target for an expected commercial launch in Q4 2017 for the treatment of congenital plasminogen deficiency. Plans to expand Prometics plasminogen future indications were outlined, including how plasminogen could significantly contribute to the rapid recovery of critically hill or injured patients such as severe burns and Acute Lung Injury. The clinical program designed to validate such future medical uses is underway as well the clinical trials for tympanic repair and diabetic foot ulcers. The Company has strengthened its financial position through a combination of transactions announced in the past several weeks, including a $25 million loan funding, and $23 million in payments to be received in 2017 from a license to certain small molecule rights in China. Moreover, the first quarter financial results are expected to be in line with recent performance, including revenues, a slight drop in R expense and EBITDA loss.
Prometic anticipates additional cash inflow to materialize in 2017 and is now well positioned to continue advancing its lead clinical programs and pursue licensing and partnership opportunities. During the presentation, management confirmed that they anticipated delivering on the following milestones for 2017: For its small molecule PBI 4050 drug candidate, ProMetic plans to: Initiate two placebo controlled phase 2/3 pivotal clinical trials in IPF patients and one phase 2/3 placebo controlled clinical trial in CKD patients with minimal financial impact in 2017; Provide additional efficacy readout from the ongoing UK open label phase 2 clinical trial and expand the clinical program to the US for patients suffering from Alstrm syndrome; Complete enrolment of the cystic fibrosis patients in the ongoing phase 2 placebo controlled cystic fibrosis related diabetes trial; and Complete enrolment of the PBI 4050 metabolic syndrome and type 2 diabetes phase 2 placebo controlled clinical trial; and Initiate a phase 1 clinical trial with PBI 4547, an analogue of PBI 4050 earmarked for NASH. For plasminogen, ProMetic anticipates to: Secure FDA approval for louis vuitton keychain amazon the use of plasminogen in patients suffering from plasminogen congenital deficiency; Complete the 36 weeks additional follow up period from the phase 2/3 clinical trial for the use of plasminogen in patients suffering from plasminogen congenital deficiency; File for regulatory approval in Canada; and Initiate phase louis vuitton purses in paris france 2 clinical programs in patients suffering from acquired plasminogen deficiencies and in patients suffering from hard to treat wounds and tympanic perforations.
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